Cleanroom Climate Control
Precision Temperature and Humidity Systems for Regulated Cleanroom Environments
Cleanrooms aren’t just spaces — they’re engineered environments where everything is controlled, measured, and validated. At Laboratory Temperature Control, we specialise in delivering climate control systems tailored specifically for cleanrooms operating in pharmaceutical, biotech, electronics, aerospace, and medical
manufacturing environments.
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If you’re designing a new cleanroom, upgrading for Annex 1 compliance, or looking to improve your current environmental stability, our team is here to help.
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Why Cleanroom Climate Control Needs a Specialist Approach
In standard HVAC, “close enough” might be good enough. But in a cleanroom, even
small fluctuations in temperature or humidity can cause contamination risks, product
failures, or compliance issues. That’s why we approach cleanroom climate control as
a specialist discipline — one that requires technical experience, careful integration,
and regulatory foresight.
Our systems are designed to deliver tight tolerances, typically within ±1°C for
temperature and ±5% for relative humidity, and often much tighter when required.
We take into account not just the size of the space, but also air changes per hour
(ACH), equipment heat loads, personnel traffic, gowning zones, and any
localised environmental conditions that could influence control.
Fully Integrated, Precision-Controlled Environments
Whether you’re running a sterile pharmaceutical fill line, a Grade B cleanroom in a biotech facility, or a Class 100 assembly area in microelectronics, we tailor each system to your exact specifications.
We can provide:
- Temperature and humidity control systems designed for ISO Class 5–8 or GMP Grade A–D cleanrooms
- Integrated air handling units (AHUs) with HEPA filtration and zone-specific control
- Dehumidification or humidification systems for static-sensitive or moisture- critical applications
- Pressure cascade management between rooms and zones
- BMS integration with real-time environmental data and remote access
- Redundant systems for validated uptime requirements
And we don’t just install the hardware — we ensure the system works in practice, not just on paper. That means full commissioning, calibration, and validation documentation aligned with your quality systems.
Designed for Compliance from Day One
We’re fully versed in the regulatory frameworks that govern cleanroom
environments, including EU GMP Annex 1, ISO 14644, FDA cGMP, and various
industry-specific guidelines. Whether you're preparing for a regulatory inspection or maintaining an accredited production line, we make sure the environmental system
supports your compliance obligations.
That includes supplying all the documentation you need for qualification and
inspection:
- User Requirement Specifications (URS)
- Functional and Design Specifications (FDS)
- Installation/Operational Qualification (IQ/OQ)
- Performance Qualification (PQ), including temperature/humidity mapping
- Alarm system validation and BMS testing
- Calibration certificates and ongoing maintenance logs
We’re happy to work directly with your QA team, cleanroom consultants, or
validation partner, or take the lead in developing compliant documentation where
needed.
Flexible Systems for All Cleanroom Types
Our cleanroom climate systems are installed in a wide variety of environments, including:
- Pharmaceutical production and packaging
- Biotechnology R&D and clean production suites
- Sterile fill-finish and aseptic manufacturing
- Medical device assembly
- Microelectronics and optical engineering
- Aerospace and satellite component testing
- Controlled clean laboratories and precision testing rooms
Whether you're designing a new cleanroom, expanding an existing one, or retrofitting to improve performance, we’ll deliver a system that works seamlessly with your facility’s needs.
Cleanroom Delivery, Done Right
We know that cleanroom environments often involve multiple contractors,
compressed timelines, and high regulatory pressure. That’s why we work flexibly —
as principal contractor, M&E specialist, or climate control subcontractor —
depending on your project setup.
We coordinate with builders, architects, cleanroom specialists and internal
engineering teams to ensure installation is smooth, compliant, and safe for GMP or
ISO operation.
We also provide long-term support after installation, including:
- Planned Preventative Maintenance (PPM)
- Filter change schedules and airflow rebalancing
- Environmental requalification and mapping
- Sensor recalibration and software updates
- Emergency call-out for faults or excursions
Serving the UK and European Cleanroom Market
From high-spec facilities in Cambridge to multi-zone production spaces in the Netherlands or Ireland, our systems operate across the UK and Western Europe. We're experienced in delivering projects under both UK and EU regulatory regimes and can adapt to your corporate or international quality system as needed.
